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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF7
All Species:
34.24
Human Site:
S124
Identified Species:
75.33
UniProt:
Q8N684
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N684
NP_001129512.1
471
52050
S124
E
N
R
A
N
G
Q
S
K
G
Y
A
E
V
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082435
519
57231
S191
Y
A
E
V
V
V
A
S
E
N
S
V
H
K
L
Dog
Lupus familis
XP_533274
514
56498
S176
E
N
R
A
N
G
Q
S
K
G
Y
A
E
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTV2
471
51993
S124
E
N
R
A
N
G
Q
S
K
G
Y
A
E
V
V
Rat
Rattus norvegicus
Q5XI29
462
51054
S124
E
N
R
A
N
G
Q
S
K
G
Y
A
E
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZL34
551
59341
S123
E
N
R
A
N
G
Q
S
K
G
F
A
L
V
G
Frog
Xenopus laevis
Q6DDW4
548
59387
S123
E
N
R
A
N
G
Q
S
K
G
F
A
L
I
C
Zebra Danio
Brachydanio rerio
Q6NWC6
545
58757
S123
E
N
R
A
N
G
Q
S
K
G
F
A
L
V
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VSH4
652
71076
S135
E
N
R
A
N
G
Q
S
K
G
F
S
V
I
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_501551
489
53643
S128
E
N
R
T
N
G
Q
S
K
G
Y
A
L
L
V
Sea Urchin
Strong. purpuratus
XP_782654
898
96357
A155
F
D
Q
A
S
K
K
A
Q
D
S
R
E
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
83.2
89.4
N.A.
98.7
96.5
N.A.
N.A.
44.2
43.9
44.5
N.A.
34.8
N.A.
31.2
21.8
Protein Similarity:
100
N.A.
84.3
89.8
N.A.
99.3
97.2
N.A.
N.A.
56.8
56.2
58.1
N.A.
46.1
N.A.
47.4
34.5
P-Site Identity:
100
N.A.
6.6
100
N.A.
100
100
N.A.
N.A.
80
73.3
80
N.A.
66.6
N.A.
80
13.3
P-Site Similarity:
100
N.A.
20
100
N.A.
100
100
N.A.
N.A.
86.6
86.6
86.6
N.A.
86.6
N.A.
86.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
82
0
0
10
10
0
0
0
73
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% C
% Asp:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% D
% Glu:
82
0
10
0
0
0
0
0
10
0
0
0
46
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
37
0
0
0
0
% F
% Gly:
0
0
0
0
0
82
0
0
0
82
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% I
% Lys:
0
0
0
0
0
10
10
0
82
0
0
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
37
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
82
0
0
82
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
82
0
10
0
0
0
0
10
0
% Q
% Arg:
0
0
82
0
0
0
0
0
0
0
0
10
0
0
10
% R
% Ser:
0
0
0
0
10
0
0
91
0
0
19
10
0
0
10
% S
% Thr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
10
10
0
0
0
0
0
10
10
55
46
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
46
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _